Diazepam is N-demethylated by CYP3A4 and 2C19 for the active metabolite N-desmethyldiazepam, which is hydroxylated by CYP3A4 for the active metabolite temazepam. N-desmethyldiazepam and temazepam are both of those additional metabolized to oxazepam. Temazepam and oxazepam are largely removed by glucuronidation.Sustained repetitive firing appears re
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